Huat Chye Lim, MD, MS

Education
Fellowship, 2023 - Hematology/Oncology, UCSF
Residency, 2018 - Internal Medicine, UCSF
MD, 2015 - , University of Washington School of Medicine
MS, 2002 - Computer Science, Stanford University
BS, 2001 - Computer Science, Stanford University
Honors and Awards
  • Rachel Pearline Award, UCSF Hematology/Oncology Fellowship, 2023
  • Scholar-in-Training Award, American Association for Cancer Research, 2022
  • Chief Fellow, UCSF Hematology/Oncology Fellowship, 2021
  • Exceptional Physician Award nominee, UCSF, 2019
  • Alpha Omega Alpha, University of Washington School of Medicine, 2014
  • Gold Humanism Honor Society, University of Washington School of Medicine, 2014
Publications

  1. Turnham RE, Pitea A, Jang GM, Xu Z, Lim HC, Choi AL, Von Dollen J, Levin RS, Webber JT, McCarthy E, Hu J, Li X, Che L, Singh A, Yoon A, Chan G, Kelley RK, Swaney DL, Zhang W, Bandyopadhyay S, Theis FJ, Eckhardt M, Chen X, Shokat KM, Ideker T, Krogan NJ, Gordan JD. HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma. Cancer research 2024. PMID: 39652575


  2. Quincy Harris, Jocelin Chen, Joseph McGuire, John Gordan, Huat Chye Lim, Michael Li, Alan P. Venook, Ann C Griffin, Robin Kate Kelley. Prevalence and clinical characteristics of patients with brain metastases at diagnosis with advanced hepatocellular carcinoma in a retrospective registry. Journal of Clinical Oncology 2025. PMID:


  3. Lauer SM, Omar MH, Golkowski MG, Kenerson HL, Lee KS, Pascual BC, Lim HC, Forbush K, Smith FD, Gordan JD, Ong SE, Yeung RS, Scott JD. Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma. Cell reports 2024. PMID: 38236773


  4. Gordan JD, Keenan BP, Lim HC, Yarchoan M, Kelley RK. New Opportunities to Individualize Frontline Therapy in Advanced Stages of Hepatocellular Carcinoma. Drugs 2023. PMID: 37402062


  5. Chan GKL, Maisel S, Hwang YC, Pascual BC, Wolber RRB, Vu P, Patra KC, Bouhaddou M, Kenerson HL, Lim HC, Long D, Yeung RS, Sethupathy P, Swaney DL, Krogan NJ, Turnham RE, Riehle KJ, Scott JD, Bardeesy N, Gordan JD. Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms. eLife 2023. PMID: 36692000


  6. John Gordan, Adriana Pitea, Rigney E Turnham, Manon Eckhardt, Gwendolyn M Jang, Huat Lim, Alex L Choi, Sourav Bandyopadhyay, Danielle Swaney, Kevan Shokat, Trey Ideker, Nevan Krogan. Abstract PO017: HBV alters YAP regulation in liver cancer by remodeling PP2A complexes. Clinical Cancer Research 2022. PMID:


  7. Rigney E Turnham, Huat Chye Lim, Lucille Ferret, Katherine Lo, LeeAnn Wang, Alex Choi, John D Gordan. Abstract PO023: Uncovering hepatitis B virus-induced signaling changes in hepatocellular carcinoma. Clinical Cancer Research 2022. PMID:


  8. Huat Chye Lim, Rigney Turnham, Katherine Lo, Yeonjoo Hwang, John Gordan. Abstract PR01: Computational identification of targetable dependencies in hepatocellular carcinoma (HCC) associated with hepatitis B virus (HBV) replication. Clinical Cancer Research 2022. PMID:


  10. John D. Gordan, Adriana Pitea, Manon Eckhardt, Gwendolyn Jang, Rigney E. Turnham, Alex L M. Choi, John Von Dollen, Huat C. Lim, Elizabeth F. Thayer, R. Katie Kelley, Danielle L. Swaney, Wei Zhang, Fabian J. Theis, Trey Ideker, Nevan J. Krogan. Abstract 4891: Hepatitis B virus remodels host protein interaction networks to generate distinct cellular dependencies. Cancer research 2020. PMID:


  11. Narasimmaraj P, Lim HC, Beck KR, Lai AR. Geriatric 'Crohn-ic' Abdominal Pain: An Unusual Presentation of a Common Disease. The American journal of medicine 2019. PMID: 31331615


  12. Huat Chye Lim, John Dozier Gordan. Genomic analysis of hepatocellular carcinoma (HCC) with active hepatitis B virus (HBV) replication. Journal of Clinical Oncology 2019. PMID:


  13. Lim HC, Montesion M, Botton T, Collisson EA, Umetsu SE, Behr SC, Gordan JD, Stephens PJ, Kelley RK. Hybrid Capture-Based Tumor Sequencing and Copy Number Analysis to Confirm Origin of Metachronous Metastases in BRCA1-Mutant Cholangiocarcinoma Harboring a Novel YWHAZ-BRAF Fusion. The oncologist 2018. PMID: 29622700


  14. Lim HC, Curlin ME, Mittler JE. HIV Therapy Simulator: a graphical user interface for comparing the effectiveness of novel therapy regimens. Bioinformatics (Oxford, England) 2011. PMID: 21908542