Rohit Bose, MD, PhD

Education
Instructor, 2018 - Dept. of Medicine, Genitourinary Service, Memorial Sloan Kettering Cancer Center
Fellowship, 2016 - Advanced Oncology, Memorial Sloan Kettering Cancer Center
Fellowship, Medical Research Track, 2014 - Medical Oncology, Memorial Sloan Kettering Cancer Center
Residency, Medical Research Track, 2010 - Internal Medicine, Weill Cornell Medicine
MD/PhD, 2008 - Medicine & Molecular Genetics, University of Toronto
Honors and Awards
  • Idea Development Award, Department of Defense, Prostate Cancer Program, 2023
  • NIH DP2 New Innovator Award, NIH Common Fund, 2023
  • Research Scholar Grant, American Cancer Society, 2022
  • Bakar Aging Research Institute Investigator Award, UCSF, 2021
  • Pilot Award for Junior Investigators in Basic and Clinical/Translational Sciences, UCSF, 2020
  • Research Funding Pilot Award, UCSF, 2019
  • K08 Mentored Clinical Scientist Research Career Development Award, NIH NCI, 2018-2023
  • (Declined) Recruitment of First-Time Tenure-Track Faculty Members Award, CPRIT, 2018
  • Physician Research Training Award, Department of Defense, Prostate Cancer Research Program, 2016-2020
  • Young Investigator Award, Prostate Cancer Foundation, 2016-2019
  • Postdoctoral Research Training Award, Department of Defense, Prostate Cancer Research Program, 2013-2015
  • Young Investigator Award, ASCO / Conquer Cancer Foundation, 2013-2014
  • Dana Fellow in Biomedical Research, Clinical Scholars Training Program, Dana Foundation, Memorial Sloan Kettering Cancer Center, Dana Foundation, 2011-2013
  • John Mendelsohn Housestaff Teaching Award, Memorial Sloan Kettering Cancer Center, 2011
  • John Ruffo Graduate Fellowship for Outstanding Achievement during M.D./Ph.D., University of Toronto, 2007
  • (Declined) Jean Alloul Entrance Scholarship for M.D./Ph.D. Program, McGill University, 1999
  • Biochemistry Scholarship for Highest Academic Achievement in Dept of Biochemistry, University of Saskatchewan, 1999
  • Earl of Bessborough Prize for Most Distinguished Graduate Receiving a B.Sc., University of Saskatchewan, 1999
  • Haslam Medal for Most Distinguished Graduate of the College of Arts and Sciences, University of Saskatchewan, 1999
  • J.F. Morgan Memorial Award for Highest Academic Achievement in Dept of Microbiology & Immunology, University of Saskatchewan, 1999
  • Entrance Scholarship for Full Tuition, University of Saskatchewan, 1995
Websites
Publications
  1. Moussavi-Baygi R, Ryan MJ, Sim W, Hoelscher SB, Luga V, Chandrakumar AA, Hoes L, Cha J, Lee YS, Herm K, Doron B, Ding CKC, Stohr BA, Jin P, Nadkarni T, Fang X, Haryono M, Nguyen A, Karthaus WR, Sawyers C, Feng FY, Goodarzi H, Bose R. Stochastically Emergent Tumors offer in vivo whole genome interrogation of cancer evolution from non-malignant precursors. bioRxiv : the preprint server for biology 2025. PMID: 40166351


  2. Jindal T, Jiang C, Alhalabi O, Nizam A, Nguyen C, Talukder R, Bakaloudi D, Davidsohn M, Freeman D, Glover M, Khaki AR, Evans S, Lemke E, Bose R, Sim W, Pywell C, Basu A, Kilari D, Barata PC, Bilen MA, Zakharia Y, Milowsky MI, Shah SA, Bellmunt J, Grivas P, Emamekhoo H, Davis NB, Gupta S, Hoimes C, Campbell MT, Alva A, Koshkin VS. Genomic Biomarkers Associated with Enfortumab Vedotin Outcomes for Patients with Advanced Urothelial Carcinoma: Analysis of UNITE Study Data. European urology oncology 2024. PMID: 39709257


  3. Kwon DH, Trihy L, Darvish N, Hearst E, Sumra S, Borno HT, Bose R, Chou J, de Kouchkovsky I, Desai A, Ekstrand B, Friedlander T, Kaur G, Koshkin VS, Nesheiwat S, Sepucha K, Small EJ, Aggarwal RR, Belkora J. Patients Can Administer Mobile Audio Recordings to Increase Knowledge in Advanced Prostate Cancer. Cancer medicine 2024. PMID: 39569542


  4. Nanivadekar AC, Bose R, Petersen BA, Okorokova EV, Sarma D, Madonna TJ, Barra B, Farooqui J, Dalrymple AN, Levy I, Helm ER, Miele VJ, Boninger ML, Capogrosso M, Bensmaia SJ, Weber DJ, Fisher LE. Publisher Correction: Restoration of sensory feedback from the foot and reduction of phantom limb pain via closed-loop spinal cord stimulation. Nature biomedical engineering 2024. PMID: 38155296


  5. Nanivadekar AC, Bose R, Petersen BA, Okorokova EV, Sarma D, Madonna TJ, Barra B, Farooqui J, Dalrymple AN, Levy I, Helm ER, Miele VJ, Boninger ML, Capogrosso M, Bensmaia SJ, Weber DJ, Fisher LE. Restoration of sensory feedback from the foot and reduction of phantom limb pain via closed-loop spinal cord stimulation. Nature biomedical engineering 2023. PMID: 38097809


  6. Aggarwal R, Starzinski S, de Kouchkovsky I, Koshkin V, Bose R, Chou J, Desai A, Kwon D, Kaushal S, Trihy L, Rastogi M, Ippisch R, Aslam M, Friedlander T, Feng F, Oh D, Cheung A, Small E, Evans M, Fong L, Hope TA. Single-dose 177Lu-PSMA-617 followed by maintenance pembrolizumab in patients with metastatic castration-resistant prostate cancer: an open-label, dose-expansion, phase 1 trial. The Lancet. Oncology 2023. PMID: 37922930


  7. Jindal T, Zhang L, Deshmukh P, Reyes K, Chan E, Kumar V, Zhu X, Maldonado E, Feng S, Johnson M, Angelidakis A, Kwon D, Desai A, Borno HT, Bose R, Wong A, Hong J, Carroll P, Meng M, Porten S, Aggarwal R, Small EJ, Fong L, Chou J, Friedlander T, de Kouchkovsky I, Koshkin VS. Impact of Squamous Histology on Clinical Outcomes and Molecular Profiling in Metastatic Urothelial Carcinoma PatientsTreated With Immune Checkpoint Inhibitors or Enfortumab Vedotin. Clinical genitourinary cancer 2023. PMID: 37316414


  8. Jindal T, Zhu X, Bose R, Kumar V, Maldonado E, Deshmukh P, Shipp C, Feng S, Johnson MS, Angelidakis A, Kwon D, Borno HT, de Kouchkovsky I, Desai A, Aggarwal R, Fong L, Small EJ, Wong A, Porten S, Chou J, Friedlander T, Koshkin VS. Somatic alterations of TP53 and MDM2 associated with response to enfortumab vedotin in patients with advanced urothelial cancer. Frontiers in oncology 2023. PMID: 37091148


  9. Kwon DH, Shakhnazaryan N, Shui D, Hong JC, Mohamad O, de Kouchkovsky I, Borno HT, Bose R, Chou J, Desai A, Fong L, Friedlander TW, Koshkin VS, Aggarwal RR, Feng FY, Hope TA, Small EJ. Serial stereotactic body radiation therapy for oligometastatic prostate cancer detected by novel PET-based radiotracers. Urologic oncology 2022. PMID: 36435709


  10. Sjöström M, Zhao SG, Levy S, Zhang M, Ning Y, Shrestha R, Lundberg A, Herberts C, Foye A, Aggarwal R, Hua JT, Li H, Bergamaschi A, Maurice-Dror C, Maheshwari A, Chen S, Ng SWS, Ye W, Petricca J, Fraser M, Chesner L, Perry MD, Moreno-Rodriguez T, Chen WS, Alumkal JJ, Chou J, Morgans AK, Beer TM, Thomas GV, Gleave M, Lloyd P, Phillips T, McCarthy E, Haffner MC, Zoubeidi A, Annala M, Reiter RE, Rettig MB, Witte ON, Fong L, Bose R, Huang FW, Luo J, Bjartell A, Lang JM, Mahajan NP, Lara PN, Evans CP, Tran PT, Posadas EM, He C, Cui XL, Huang J, Zwart W, Gilbert LA, Maher CA, Boutros PC, Chi KN, Ashworth A, Small EJ, He HH, Wyatt AW, Quigley DA, Feng FY. The 5-Hydroxymethylcytosine Landscape of Prostate Cancer. Cancer research 2022. PMID: 36251389


  11. Ogura K, Elkrief A, Bowman AS, Koche RP, de Stanchina E, Benayed R, Mauguen A, Mattar MS, Khodos I, Meyers PA, Healey JH, Tap WD, Hameed M, Zehir A, Shukla N, Sawyers C, Bose R, Slotkin E, Ladanyi M. Prospective Clinical Genomic Profiling of Ewing Sarcoma: ERF and FGFR1 Mutations as Recurrent Secondary Alterations of Potential Biologic and Therapeutic Relevance. JCO precision oncology 2022. PMID: 35952322


  12. Tayeb Z, Dragomir A, Lee JH, Abbasi NI, Dean E, Bandla A, Bose R, Sundar R, Bezerianos A, Thakor NV, Cheng G. Distinct spatio-temporal and spectral brain patterns for different thermal stimuli perception. Scientific Reports 2022. PMID: 35042875


  13. Kwon DH, Karthikeyan S, Chang A, Borno HT, Koshkin VS, Desai A, Bose R, Friedlander T, Rodvelt T, Li P, Small EJ, Aggarwal RR, Belkora J. Mobile Audio Recording Technology to Promote Informed Decision Making in Advanced Prostate Cancer. JCO oncology practice 2021. PMID: 34932386


  14. Osborn LE, Ding K, Hays MA, Bose R, Iskarous MM, Dragomir A, Tayeb Z, Lévay GM, Hunt CL, Cheng G, Armiger RS, Bezerianos A, Fifer MS, Thakor NV. Sensory stimulation enhances phantom limb perception and movement decoding. Journal of neural engineering 2020. PMID: 33078717


  15. Zhao SG, Chen WS, Li H, Foye A, Zhang M, Sjöström M, Aggarwal R, Playdle D, Liao A, Alumkal JJ, Das R, Chou J, Hua JT, Barnard TJ, Bailey AM, Chow ED, Perry MD, Dang HX, Yang R, Moussavi-Baygi R, Zhang L, Alshalalfa M, Laura Chang S, Houlahan KE, Shiah YJ, Beer TM, Thomas G, Chi KN, Gleave M, Zoubeidi A, Reiter RE, Rettig MB, Witte O, Yvonne Kim M, Fong L, Spratt DE, Morgan TM, Bose R, Huang FW, Li H, Chesner L, Shenoy T, Goodarzi H, Asangani IA, Sandhu S, Lang JM, Mahajan NP, Lara PN, Evans CP, Febbo P, Batzoglou S, Knudsen KE, He HH, Huang J, Zwart W, Costello JF, Luo J, Tomlins SA, Wyatt AW, Dehm SM, Ashworth A, Gilbert LA, Boutros PC, Farh K, Chinnaiyan AM, Maher CA, Small EJ, Quigley DA, Feng FY. The DNA methylation landscape of advanced prostate cancer. Nature genetics 2020. PMID: 32661416


  16. Tayeb Z, Bose R, Dragomir A, Osborn LE, Thakor NV, Cheng G. Decoding of Pain Perception using EEG Signals for a Real-Time Reflex System in Prostheses: A Case Study. Scientific Reports 2020. PMID: 32221336


  17. Ryan MJ, Bose R. Genomic Alteration Burden in Advanced Prostate Cancer and Therapeutic Implications. Frontiers in oncology 2019. PMID: 31824860


  18. Adams EJ, Karthaus WR, Hoover E, Liu D, Gruet A, Zhang Z, Cho H, DiLoreto R, Chhangawala S, Liu Y, Watson PA, Davicioni E, Sboner A, Barbieri CE, Bose R, Leslie CS, Sawyers CL. FOXA1 mutations alter pioneering activity, differentiation and prostate cancer phenotypes. Nature 2019. PMID: 31243370


  19. Bose R, Karthaus WR, Armenia J, Abida W, Iaquinta PJ, Zhang Z, Wongvipat J, Wasmuth EV, Shah N, Sullivan PS, Doran MG, Wang P, Patruno A, Zhao Y, International SU2C/PCF Prostate Cancer Dream Team, Zheng D, Schultz N, Sawyers CL. ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis. Nature 2017. PMID: 28614298


  20. Viloria-Petit AM, David L, Jia JY, Erdemir T, Bane AL, Pinnaduwage D, Roncari L, Narimatsu M, Bose R, Moffat J, Wong JW, Kerbel RS, O'Malley FP, Andrulis IL, Wrana JL. A role for the TGFbeta-Par6 polarity pathway in breast cancer progression. Proceedings of the National Academy of Sciences of the United States of America 2009. PMID: 19667198


  21. Narimatsu M, Bose R, Pye M, Zhang L, Miller B, Ching P, Sakuma R, Luga V, Roncari L, Attisano L, Wrana JL. Regulation of planar cell polarity by Smurf ubiquitin ligases. Cell 2009. PMID: 19379695


  22. Bose R, Wrana JL. Regulation of Par6 by extracellular signals. Current opinion in cell biology 2006. PMID: 16490351


  23. Wang HR, Ogunjimi AA, Zhang Y, Ozdamar B, Bose R, Wrana JL. Degradation of RhoA by Smurf1 ubiquitin ligase. Methods in enzymology 2006. PMID: 16472676


  24. Barrios-Rodiles M, Brown KR, Ozdamar B, Bose R, Liu Z, Donovan RS, Shinjo F, Liu Y, Dembowy J, Taylor IW, Luga V, Przulj N, Robinson M, Suzuki H, Hayashizaki Y, Jurisica I, Wrana JL. High-throughput mapping of a dynamic signaling network in mammalian cells. Science (New York, N.Y.) 2005. PMID: 15761153


  25. Ozdamar B, Bose R, Barrios-Rodiles M, Wang HR, Zhang Y, Wrana JL. Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity. Science (New York, N.Y.) 2005. PMID: 15761148


  26. Bose R, Hwang SW. Income and spending patterns among panhandlers. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2002. PMID: 12240813


  27. Bose R, Ahmad A, Dicks A, Novak M, Kayser K, McClelland R. Spectroscopic characterization by laser flash photolysis of electrophilic intermediates derived from 4-aminostilbenes. Stilbene "nitrenium" ions and quinone methide imines Journal of the Chemical Society, Perkin Transactions 2 1999. PMID: