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Ann O'Hare, MD is a nephrologist and health services researcher at the University of Washington where she is a Professor in the Department of Medicine as well as a Staff Physician at the VA Puget Sound Health Care System.  She received her undergraduate degree in Geography from the University of Cambridge in England in 1985, her Masters’ degree in Geography from the University of Minnesota in Minneapolis in 1987, and her medical doctorate from the University of Virginia in Charlottesville in 1996.  She completed residency at Stanford University in Palo Alto in 1999 and Nephrology fellowship at the University of California, San Francisco in 2003.  She has served on the faculty of Medicine at the University of California, San Francisco (2003-2007) and at the University of Washington in Seattle (2007-present).  Her clinical, research and teaching interest is in how we care for older adults with kidney disease.  Her research is currently supported by the National Institutes of Health and the Department of Veterans Affairs.  Over the course of her career she has published widely on the topic of caring for older adults with kidney disease in both the nephrology and general medicine literature.  She is deeply appreciative of the many insights and opportunities for enrichment afforded by her diverse but related roles of caring for patients, conducting research and mentoring trainees and junior faculty. 

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DOM Medical Grand Rounds.

Pamela Munster, MD is a professor of medicine at the University of California, San Francisco, where at the Helen Diller Family Comprehensive Cancer Center, she is leader of the Developmental Therapeutics Program, Director of Early Phase Clinical Trials Unit, and Co-Director of the UCSF Center for BRCA Research. In Dr. Munster’s lab, UCSF scientists are exploring new ways to detect, surveil, intercept, and cure BRCA-related cancers. In addition to her laboratory research, she develops novel strategies to treat patients with incurable cancers as an oncologist. Dr. Munster serves on multiple local, national and international committees focused on developing new treatments for cancer, has published over two hundred articles, authored textbooks and is a frequent lecturer. A native of Switzerland, she leads breast cancer awareness campaigns in the United States, United Arab Emirates, and India.

Dr. Munster was diagnosed with a BRCA2 mutation in 2012. There was not an easy place to coordinate her care, and so she set out to create the UCSF Center for BRCA Research in partnership with Alan Ashworth, PhD, FRS. By transcending the doctor-patient perspective, Dr. Munster gives a framework for successful treatment – epitomizing the personal, patient centered care that is a hallmark of the UCSF medical center. Dr. Munster recently authored Twisting Fate, about her experience as an oncologist and a cancer patient.

To access MGR live streams and current semester recordings, please visit ETS here: DOM Medical Grand Rounds.

Chloe E. Atreya, MD, PhD is an Assistant Professor in the Department of Medicine, Division of Hematology and Oncology, and a UCSF Osher Center for Integrative Medicine affiliated faculty member.  Chloe is a physician scientist with expertise in bridging clinical practice and research. Her overall focus is on personalizing care for patients with metastatic colorectal cancer. Current projects include studying the impact of the gut microbiome on metabolism of oral chemotherapy, investigator-initiated clinical/pre-clinical trials of novel drug therapies, and development and implementation of the Being Present mindfulness meditation program. Her ultimate objectives are to improve outcomes and quality of life for patients with advanced cancer and also to support caregivers.

To access MGR live streams and current semester recordings, please visit ETS here: DOM Medical Grand Rounds.

Lisa Tran

David Tuveson is Director of the Cancer Center and the Roy J. Zuckerberg Professor of Cancer Research at Cold Spring Harbor 

PLEASE NOTE THAT THIS GRAND ROUNDS IS BEING HELD IN COLE HALL, NOT HSW-301 

To access MGR live streams and current semester recordings, please visit ETS here: DOM Medical Grand Rounds.

Kimberly Dyan Manning, MD, FACP, FAAP

Kimberly D. Manning, MD is an Associate Professor of Medicine and the Associate Vice Chair of Diversity, Equity, and Inclusion in the Department of Medicine at Emory University School of Medicine.  Dr. Manning is a general internist/hospitalist who serves as residency program director for the Transitional Year Residency Program and is one of a small number of faculty appointed to lead the medical school curriculum as a small group advisor.

Dr. Manning’s academic achievements include numerous institutional, regional and national teaching awards. She has a strong passion for building and strengthening diverse clinical learning environments as well as cultivating psychologically safe learning climates.

An avid teacher, Dr. Manning regularly speaks at community events and podcasts and has taught at several national and international medical conferences as an invited lecturer. But most of all, she enjoys the everyday of teaching patients, students, and residents at Grady Memorial Hospital. Additionally, she is a prolific writer and authors a blog called “Reflections of a Grady Doctor” which was named in 2010 by ‘O’ The Oprah Magazine as one of 4 medical blogs you should read.

PLEASE NOTE THAT THIS GRAND ROUNDS IS BEING HELD IN HSW-301 

To access MGR live streams and current semester recordings, please visit ETS here: DOM Medical Grand Rounds.

David A. Tuveson MD, PhD

David Tuveson is Director of the Cancer Center and the Roy J. Zuckerberg Professor of Cancer Research at Cold Spring Harbor Laboratory, and the Chief Scientist at the Lustgarten Foundation.  Dr. Tuveson obtained a bachelors degree in chemistry at M.I.T., followed by M.D. and Ph.D. degrees at Johns Hopkins. Dr. Tuveson was a medical resident at Brigham and Women’s Hospital and a medical oncology fellow at Dana-Farber/Harvard Cancer Center.  During his post-doctoral years in Boston, Dr. Tuveson co-developed KIT inhibitors for gastrointestinal stromal tumors with George Demetri.  Simultaneously, he generated several widely-used mouse cancer models with Tyler Jacks.  As an independent investigator, his lab developed the first mouse models of ductal pancreatic cancer at the University of Pennsylvania.  Subsequently, Dr. Tuveson was recruited to the University of Cambridge where his lab identified poor drug delivery as a barrier for therapeutic efficacy in pancreatic cancer.  He was then recruited to CSHL as the Deputy Director of the Cancer Center and to serve as Director of Research for the Lustgarten Foundation.  At CSHL, his lab co-developed pancreatic organoid cancer models with Hans Clevers, and made a series of observations regarding cancer fibroblasts, redox regulation, and pancreatitis. His awards include the Rita Allen Scholarship and the Jan Waldenström Award, and the Hamdan Award.

PLEASE NOTE THAT THIS GRAND ROUNDS IS BEING HELD IN COLE HALL, NOT HSW-301 

To access MGR live streams and current semester recordings, please visit ETS here: DOM Medical Grand Rounds.

Objectives:

• Review updates in the management of breast cancer
• Incorporating genomic data in breast cancer management
• New therapies and paradigms in breast cancer management
• Discuss the landscape of breast cancer in San Francisco

Robert M. Wachter, MD is Professor and Chair of the Department of Medicine at the University of California, San Francisco, where he is the Holly Smith Distinguished Professor in Science and Medicine and the Benioff Endowed Chair in Hospital Medicine. The department leads the nation in NIH grants and is generally ranked as one of the nation’s best.

Wachter is author of 250 articles and 6 books and is a frequent contributor to the New York Times and Wall Street Journal. He coined the term “hospitalist” in 1996 and is often considered the “father” of the hospitalist field, the fastest growing specialty in the history of modern medicine. He is past president of the Society of Hospital Medicine and past chair of the American Board of Internal Medicine.

In the safety and quality arenas, he edits the U.S. government’s leading website on patient safety and has written two books on the subject, including Understanding Patient Safety, the world’s top selling safety primer. In 2004, he received the John M. Eisenberg Award, the nation’s top honor in patient safety. Twelve times, Modern Healthcare magazine has ranked him as one of the 50 most influential physician-executives in the U.S.; he was #1 on the list in 2015. His 2015 book, The Digital Doctor: Hope, Hype and Harm at the Dawn of Medicine’s Computer Age, was a New York Times science bestseller. In 2016, he chaired a blue-ribbon commission advising England’s National Health Service on its digital strategy.

.To access MGR live streams and current semester recordings, please visit ETS here: DOM Medical Grand Rounds.

Lawrence Fong is a Professor in Residence in the Division of Hematology/Oncology.

To access MGR live streams and current semester recordings, please visit ETS here: DOM Medical Grand Rounds.