Hematology and Oncology

Pamela Munster, MD is a professor of medicine at the University of California, San Francisco, where at the Helen Diller Family Comprehensive Cancer Center, she is leader of the Developmental Therapeutics Program, Director of Early Phase Clinical Trials Unit, and Co-Director of the UCSF Center for BRCA Research. In Dr. Munster’s lab, UCSF scientists are exploring new ways to detect, surveil, intercept, and cure BRCA-related cancers. In addition to her laboratory research, she develops novel strategies to treat patients with incurable cancers as an oncologist. Dr. Munster serves on multiple local, national and international committees focused on developing new treatments for cancer, has published over two hundred articles, authored textbooks and is a frequent lecturer. A native of Switzerland, she leads breast cancer awareness campaigns in the United States, United Arab Emirates, and India.

Dr. Munster was diagnosed with a BRCA2 mutation in 2012. There was not an easy place to coordinate her care, and so she set out to create the UCSF Center for BRCA Research in partnership with Alan Ashworth, PhD, FRS. By transcending the doctor-patient perspective, Dr. Munster gives a framework for successful treatment – epitomizing the personal, patient centered care that is a hallmark of the UCSF medical center. Dr. Munster recently authored Twisting Fate, about her experience as an oncologist and a cancer patient.

To access MGR live streams and current semester recordings, please visit ETS here: DOM Medical Grand Rounds.

/Kimberly Dyan Manning, MD, FACP, FAAP

Kimberly D. Manning, MD is a general internist/hospitalist who serves as an Associate Professor of Medicine and Associate Vice Chair of Diversity, Equity, and Inclusion for the Department of Medicine at Emory University School of Medicine.  Manning additionally serves as residency program director for the Transitional Year Residency Program and is one of a small number of faculty appointed to lead the medical school curriculum as a small group advisor.

Manning’s academic achievements include numerous institutional, regional and national teaching awards. She has a strong passion for building and strengthening diverse clinical learning environments as well as cultivating psychologically safe learning climates.

An avid teacher, she regularly speaks at community events, on podcasts and has taught at several National and International Medical conferences as an invited lecturer. But most of all, she enjoys the everyday of teaching patients, students, and residents at Grady Memorial Hospital. Additionally, she is a prolific writer and authors a blog called “Reflections of a Grady Doctor” which was named in 2010 by ‘O’ The Oprah Magazine as one of 4 medical blogs you should read.

The Los Angeles area native is a proud alumnus of both Tuskegee University and Meharry Medical College.

PLEASE NOTE THAT THIS GRAND ROUNDS IS BEING HELD IN HSW-301 

To access MGR live streams and current semester recordings, please visit ETS here: DOM Medical Grand Rounds.

David A. Tuveson MD, PhD

David Tuveson is Director of the Cancer Center and the Roy J. Zuckerberg Professor of Cancer Research at Cold Spring Harbor Laboratory, and the Chief Scientist at the Lustgarten Foundation.  Dr. Tuveson obtained a bachelors degree in chemistry at M.I.T., followed by M.D. and Ph.D. degrees at Johns Hopkins. Dr. Tuveson was a medical resident at Brigham and Women’s Hospital and a medical oncology fellow at Dana-Farber/Harvard Cancer Center.  During his post-doctoral years in Boston, Dr. Tuveson co-developed KIT inhibitors for gastrointestinal stromal tumors with George Demetri.  Simultaneously, he generated several widely-used mouse cancer models with Tyler Jacks.  As an independent investigator, his lab developed the first mouse models of ductal pancreatic cancer at the University of Pennsylvania.  Subsequently, Dr. Tuveson was recruited to the University of Cambridge where his lab identified poor drug delivery as a barrier for therapeutic efficacy in pancreatic cancer.  He was then recruited to CSHL as the Deputy Director of the Cancer Center and to serve as Director of Research for the Lustgarten Foundation.  At CSHL, his lab co-developed pancreatic organoid cancer models with Hans Clevers, and made a series of observations regarding cancer fibroblasts, redox regulation, and pancreatitis. His awards include the Rita Allen Scholarship and the Jan Waldenström Award, and the Hamdan Award.

PLEASE NOTE THAT THIS GRAND ROUNDS IS BEING HELD IN COLE HALL, NOT HSW-301 

To access MGR live streams and current semester recordings, please visit ETS here: DOM Medical Grand Rounds.

Objectives:

• Review updates in the management of breast cancer
• Incorporating genomic data in breast cancer management
• New therapies and paradigms in breast cancer management
• Discuss the landscape of breast cancer in San Francisco

Robert M. Wachter, MD is Professor and Chair of the Department of Medicine at the University of California, San Francisco, where he is the Holly Smith Distinguished Professor in Science and Medicine and the Benioff Endowed Chair in Hospital Medicine. The department leads the nation in NIH grants and is generally ranked as one of the nation’s best.

Wachter is author of 250 articles and 6 books and is a frequent contributor to the New York Times and Wall Street Journal. He coined the term “hospitalist” in 1996 and is often considered the “father” of the hospitalist field, the fastest growing specialty in the history of modern medicine. He is past president of the Society of Hospital Medicine and past chair of the American Board of Internal Medicine.

In the safety and quality arenas, he edits the U.S. government’s leading website on patient safety and has written two books on the subject, including Understanding Patient Safety, the world’s top selling safety primer. In 2004, he received the John M. Eisenberg Award, the nation’s top honor in patient safety. Twelve times, Modern Healthcare magazine has ranked him as one of the 50 most influential physician-executives in the U.S.; he was #1 on the list in 2015. His 2015 book, The Digital Doctor: Hope, Hype and Harm at the Dawn of Medicine’s Computer Age, was a New York Times science bestseller. In 2016, he chaired a blue-ribbon commission advising England’s National Health Service on its digital strategy.

.To access MGR live streams and current semester recordings, please visit ETS here: DOM Medical Grand Rounds.